A network-based approach to uncover microRNA-mediated disease comorbidities and potential pathobiological implications

Shuting Jin, Xiangxiang Zeng, Jiansong Fang, Jiawei Lin, Stephen Y. Chan, Serpil C. Erzurum & Feixiong Cheng; npj Syst Biol Appl 5, 41 (2019) doi:10.1038/s41540-019-0115-2

Beyond genetic analysis, shared patterns of gene expression have raised possibilities to inspect disease–disease relationships.6 Alteration and dysregulation of gene expressions are caused by several biological mechanisms, including microRNA (miRNA) dysregulation.