Saturday, May 2, 2009

Dendrimers as synthetic gene vectors: Cell membrane attachment

J. Chem. Phys. 130, 155101 (2009); DOI:10.1063/1.3109902 Published 16 April 2009

N. K. Voulgarakis, K. Ø. Rasmussen, and P. M. Welch
Theoretical Division and Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA

Dendrimers as synthetic gene vectors: Cell membrane attachment






First Large-Scale Computer Simulation Of Gene Therapy

http://www.medicalnewstoday.com/articles/148319.php

First Large-Scale Computer Simulation Of Gene Therapy

Effectiveness and safety of treatments for degenerative ataxias: A systematic review

http://www3.interscience.wiley.com/journal/122371107/abstract?CRETRY=1&SRETRY=0

Effectiveness and safety of treatments for degenerative ataxias: A systematic review


M.Mar Trujillo-Martín, PhD 1 *, Pedro Serrano-Aguilar, MD, PhD 2 3, Fernando Monton-Álvarez, MD, PhD 4, Romen Carrillo-Fumero, PhD 1
1Canary Islands Research and Health Foundation (Fundación Canaria de Investigación y Salud-FUNCIS), Santa Cruz de Tenerife, Canary Islands, Spain
2Planning and Evaluation Unit, Canary Islands Health Authority, Santa Cruz de Tenerife, Canary Islands, Spain
3CIBER Epidemiología y Salud Pública (CIBERESP), Spain
4Department of Neurology, University Hospital of Na Sa de la Candelaria, Santa Cruz de Tenerife, Canary Islands, Spain
email: M.Mar Trujillo-Martín (matrumar@gobiernodecanarias.org)

*Correspondence to M.Mar Trujillo-Martín, Servicio de Evaluación y Planificación, Servicio Canario de la Salud, Pérez de Rozas, 5-4a planta, 38004 Santa Cruz de Tenerife, España

Potential conflict of interest: None reported.

Funded by:
Spanish Ministry of Health
Consumption in cooperation
Fundación Canaria de Investigación y Salud (FUNCIS)

Keywords
rare diseases • degenerative ataxia • systematic review • treatment effectiveness • treatment safety
Received: 13 October 2008; Accepted: 3 March 2009
Digital Object Identifier (DOI)



Evidence That Phosphorylation of Iron Regulatory Protein 1 at Serine 138 Destabilizes the [4Fe-4S] Cluster in Cytosolic Aconitase by Enhancing 4Fe-3Fe

Originally published In Press as doi:10.1074/jbc.M807717200 on March 6, 2009 J. Biol. Chem., Vol. 284, Issue 19, 12701-12709, May 8, 2009

Evidence That Phosphorylation of Iron Regulatory Protein 1 at Serine 138 Destabilizes the [4Fe-4S] Cluster in Cytosolic Aconitase by Enhancing 4Fe-3Fe Cycling*Formula

Kathryn M. Deck{ddagger}, Aparna Vasanthakumar{ddagger}, Sheila A. Anderson{ddagger}, Jeremy B. Goforth{ddagger}1, M. Claire Kennedy§, William E. Antholine, and Richard S. Eisenstein{ddagger}2

From the {ddagger}Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706, the §Biochemistry Department, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, and the National Biomedical ESR Center, Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226-3548

Received for publication, October 6, 2008 , and in revised form, March 5, 2009.

This paper is dedicated to the memory of Helmut Beinert.

* This work was supported in part by National Institutes of Health Grants DK 66600 (to R. S. E.) and National Biomedical ESR Center Grant EB001980. This work was also supported by United States Department of Agriculture Cooperative States Research Education and Extension Service Grant 2006-35200-16604 and University of Wisconsin-Madison Hatch Project 4885 (to R. S. E.).

Formula The on-line version of this article (available at http://www.jbc.org/) contains supplemental Figs. S1 and S2.

1 Supported by National Institutes of Health Training Grant T32 DK007665.

2 To whom correspondence should be addressed: University of Wisconsin, Dept. of Nutritional Sciences, 1415 Linden Dr., Madison, WI 53706. Tel.: 608-262-5830; Fax: 608-262-5860; E-mail: eisenste@nutrisci.wisc.edu
.