Peverill RE, Donelan L, Corben LA, Delatycki MB (2018). PLoS ONE 13(12): e0209410. doi:10.1371/journal.pone.0209410
There are generalized abnormalities of RV and LV regional long axis function in FRDA, but there are also regional differences in the association of the various LV walls long-axis TDI velocities with the small and large alleles of the FXN gene and the extent of LV structural change. Further studies are required to confirm these findings and to investigate possible mechanisms which might explain these regional LV and RV differences.
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