Thursday, May 7, 2009

p53/CEP-1 Increases or Decreases Lifespan, Depending on Level of Mitochondrial Bioenergetic Stress.

Aging Cell. 2009 Apr 22. [Epub ahead of print]

p53/CEP-1 Increases or Decreases Lifespan, Depending on Level of Mitochondrial Bioenergetic Stress.

Ventura N, Rea SL, Schiavi A, Torgovnick A, Testi R, Johnson TE.
Institute for Behavioral Genetics, University of Colorado at Boulder, Box 447, Boulder, CO 80309, USA.

Oxidative stress induces degradation of mitochondrial DNA

http://nar.oxfordjournals.org/cgi/content/short/37/8/2539?rss=1

http://nar.oxfordjournals.org/cgi/reprint/37/8/2539 (Full text)

Nucleic Acids Research Advance Access originally published online on March 5, 2009 Nucleic Acids Research 2009 37(8):2539-2548; doi:10.1093/nar/gkp100

Oxidative stress induces degradation of mitochondrial DNA

Inna Shokolenko, Natalia Venediktova, Alexandra Bochkareva, Glenn L. Wilson and Mikhail F. Alexeyev*
Department of Cell Biology and Neuroscience, University of South Alabama, Mobile, AL 36688, USA
*To whom correspondence should be addressed. Tel: +1 251 460 6789; Fax: +1 251 460 6771; Email: malexeye@jaguar1.usouthal.edu

Received September 4, 2008. Revised January 25, 2009. Accepted February 8, 2009.

Fly Study Suggests That Gene May 'Bypass' Disease-Linked Mitochondrial Defects

Fly Study Suggests That Gene May 'Bypass' Disease-Linked Mitochondrial Defects

Article Date: 06 May 2009 - 6:00 PDT
http://www.medicalnewstoday.com/articles/149070.php