Oxidative stress induces degradation of mitochondrial DNA

http://nar.oxfordjournals.org/cgi/content/short/37/8/2539?rss=1

http://nar.oxfordjournals.org/cgi/reprint/37/8/2539 (Full text)

Nucleic Acids Research Advance Access originally published online on March 5, 2009 Nucleic Acids Research 2009 37(8):2539-2548; doi:10.1093/nar/gkp100

Oxidative stress induces degradation of mitochondrial DNA

Inna Shokolenko, Natalia Venediktova, Alexandra Bochkareva, Glenn L. Wilson and Mikhail F. Alexeyev*
Department of Cell Biology and Neuroscience, University of South Alabama, Mobile, AL 36688, USA
*To whom correspondence should be addressed. Tel: +1 251 460 6789; Fax: +1 251 460 6771; Email: malexeye@jaguar1.usouthal.edu

Received September 4, 2008. Revised January 25, 2009. Accepted February 8, 2009.