Monday, March 4, 2013

Friedreich's ataxia–associated GAA repeats induce replication-fork reversal and unusual molecular junctions

Friedreich's ataxia–associated GAA repeats induce replication-fork reversal and unusual molecular junctions. Cindy Follonier, Judith Oehler, Raquel Herrador & Massimo Lopes. Nature Structural & Molecular Biology (2013), Published online 03 March 2013, doi:10.1038/nsmb.2520

Keywords: Expansion of GAA/TTC repeats, mechanisms of replication interference and expansion, in vivo replication structures at GAA repeats, replication-associated intramolecular junctions, homopurine-homopyrimidine tracts, postreplicative mechanisms.