Monday, June 9, 2014

HDAC Inhibition Appears Safe in Early Trial on Friedreich's Ataxia

HDAC Inhibition Appears Safe in Early Trial on Friedreich's Ataxia, NEWS FROM THE AAN ANNUAL MEETING. Neurology Today:
5 June 2014 - Volume 14 - Issue 11 - p 46-47, doi: 10.1097/01.NT.0000451003.10471.a7

In a phase 1 trial, a histone deacetylase inhibitor appears to be safe and to increase expression of the frataxin gene in adult patients with Friedreich's ataxia.