Sunday, March 22, 2015

Gene and cell therapy for neurogenetic disease: hope through research

Gene and cell therapy for neurogenetic disease: hope through research. INTERNATIONAL INNOVATION, Dr Marguerite Evans-Galea PhD, Murdoch Childrens Research Institute, Melbourne, Australia; Executive Member, Australasian Gene and Cell Therapy Society

AMELIORATION OF THE EFFECTS OF FRIEDRIECH'S ATAXIA .

AMELIORATION OF THE EFFECTS OF FRIEDRIECH'S ATAXIA. Applicants: WILSON, Robert, B., COTTICELLI, M., Grazia CRABBE, Andrew, M. Publication Date: 26.02.2015

The effects of Friedreich's Ataxia are ameliorated by administering to a patient known or suspected of having the disease with essentially free cis Δ9 fatty acid having from 12 to 24 carbon atoms and a single double bond in a cis configuration at the C9 carbon atom

Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes.

Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes. Thomas Eschenhagen, Christine Mummery and Bjorn C. Knollmann. Cardiovasc Res. 2015 April 1; 105(4): 424–438. doi: 10.1093/cvr/cvv017

FULL TEXT PDF Available in Europe PMC (Free)

Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications

Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications. Nadezda Apostolova and Victor M. Victor; Antioxid Redox Signal. 2015 March 10; 22(8): 686–729. doi: 10.1089/ars.2014.5952

FULL TEXT PDF Available in Europe PMC (Free)

Abnormal Cochlear Potentials in Friedreich's Ataxia Point to Disordered Synchrony of Auditory Nerve Fiber Activity

Abnormal Cochlear Potentials in Friedreich's Ataxia Point to Disordered Synchrony of Auditory Nerve Fiber Activity. Santarelli R., Cama E., Pegoraro E., Scimemi P.; Neurodegenerative Diseases, Vol. 0, No. 0, Year 2015 (Cover Date: Online First), DOI:10.1159/000375307

A longitudinal study of the Friedreich Ataxia Impact Scale

A longitudinal study of the Friedreich Ataxia Impact Scale; Geneieve Tai, Eppie M. Yiu, Louise A. Corben, Martin B. Delatycki, Journal of the Neurological Sciences, Available online 21 March 2015, ISSN 0022-510X, http://dx.doi.org/10.1016/j.jns.2015.03.024.