Energy failure—does it contribute to neurodegeneration?

Energy failure—does it contribute to neurodegeneration?. Divya Pathak, Amandine Berthet and Ken Nakamura; Annals of Neurology, Accepted manuscript online: 22 AUG 2013 04:13PM EST | DOI: 10.1002/ana.24014

Energy failure has never been directly demonstrated in affected neurons in these diseases, nor has it been proved to produce degeneration in disease models but energy failure from mitochondrial dysfunction is proposed to be a central mechanism leading to neuronal death in a range of neurodegenerative diseases.

Widespread and enzyme-independent N ε - acet ylation and N ε -succinylation of proteins in the chemical conditions of the mitochondrial matrix

Widespread and enzyme-independent Nε-acetylation and Nε-succinylation of proteins in the chemicalconditions of the mitochondrial matrix. Gregory R. Wagner and R. Mark Payne; J. Biol. Chem. jbc.M113.486753. First Published on August 13, 2013, doi:10.1074/jbc.M113.486753

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Quantitative profiling and identification of differentially expressed plasma proteins in friedreich's ataxia

Quantitative profiling and identification of differentially expressed plasma proteins in friedreich's ataxia. Swarup, V., Srivastava, A. K., Padma, M. V. and Rajeswari, M. R.; J. Neurosci. Res.. doi: 10.1002/jnr.23262

Keywords: Friedreich's ataxia (FRDA), plasma proteins, α1-antitrypsin, apolipoprotein A-I, albumin, apolipoprotein C-II, C-III.