The Fitts task reveals impairments in planning and online control of movement in Friedreich ataxia: reduced cerebellar-cortico connectivity?

Neuroscience, doi:10.1016/j.neuroscience.2011.06.057, Available online 25 June 2011.

Louise A. Corben 1, 2, Nellie Georgiou-Karistianis 2, John L. Bradshaw 2, Darren R. Hocking 3, Andrew J. Churchyard 4 and Martin B. Delatycki 1, 5, 6

1 Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Parkville, Victoria, Australia
2 Experimental Neuropsychology Research Unit, School of Psychology and, Psychiatry, Monash University, Clayton, Victoria, Australia
3 Developmental Neuroscience and Genetic Disorders Laboratory, School of Psychology and Psychiatry, Monash University, Clayton, Victoria, Australia
4 Monash Neurology, Monash Medical Centre, Clayton, Victoria, Australia
5 Department of Clinical Genetics, Austin Health, Heidelberg, Victoria, Australia
6 Department of Medicine, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia

KEYWORDS: Friedreich ataxia (FRDA), cognitive and/or psychomotor capacity, cerebellum, cortex, Fitts’ Law, preplanning of movement, online error detection and correction, prefrontal/anterior regions.

Case Report : Massive uterine leiomyoma in a patient with Friedreich’s ataxia: Is there a possible association?

Case Reports in Medicine, Received 26 May 2011; Accepted 24 June 2011

Evangelos Misiakos, Elli Siama, Dimitrios Schizas, Constantinos Petropoulos, Nick Zavras, Nikos Economopoulos, Alexandros Charalabopoulos, and Anastasios N. Macheras
University of Athens School of Medicine, Athens, Greece.

KEYWORDS: Friedreich’s ataxia, leiomyoma, intestinal obstruction, tumor excision, adhesionlysis, "neoplasms uncommon for their young age".

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