Biochemistry (Mosc). 2012 Feb;77(2):135-42.
Wu G, Li L.
College of Life Science, Zhejiang University, Hangzhou, 310058, China.
Keywords: Iron-sulfur cluster, IscU, iron, cysteine, environmental pH, IscS, first order reaction, mixed order reaction, zero order reaction, apo-IscU.
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Wednesday, February 22, 2012
Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis
Biochemistry, Just Accepted Manuscript, DOI: 10.1021/bi201628j, Publication Date (Web): February 21, 2012
Jennifer Bridwell-Rabb, Clara Iannuzzi, Annalisa Pastore, and David P. Barondeau
Keywords: frataxin (FXN), Friedreich’s ataxia, NFS1-ISD11-ISCU2-FXN (SDUF) core Fe-S assembly complex, cysteine desulfurase, Fe-S cluster biosynthesis.
Jennifer Bridwell-Rabb, Clara Iannuzzi, Annalisa Pastore, and David P. Barondeau
Keywords: frataxin (FXN), Friedreich’s ataxia, NFS1-ISD11-ISCU2-FXN (SDUF) core Fe-S assembly complex, cysteine desulfurase, Fe-S cluster biosynthesis.
Cognition in Friedreich Ataxia.
Cerebellum. 2012 Feb 16.
Nieto A, Correia R, de Nóbrega E, Montón F, Hess S, Barroso J.
School of Psychology, University of La Laguna, 38205, La Laguna, Tenerife, Spain,
Keywords: Friedreich ataxia (FRDA), cognitive status, motor problems, processing speed, attention, working memory, executive functions, verbal and visual memory, visuoperceptive and visuospatial skills, visuoconstructive functions, language, depression inventory, executive problems, parieto-temporal dysfunction, mild anomalies in cerebral hemispheres, cerebro-cerebellar circuits..
Nieto A, Correia R, de Nóbrega E, Montón F, Hess S, Barroso J.
School of Psychology, University of La Laguna, 38205, La Laguna, Tenerife, Spain,
Keywords: Friedreich ataxia (FRDA), cognitive status, motor problems, processing speed, attention, working memory, executive functions, verbal and visual memory, visuoperceptive and visuospatial skills, visuoconstructive functions, language, depression inventory, executive problems, parieto-temporal dysfunction, mild anomalies in cerebral hemispheres, cerebro-cerebellar circuits..
Histone Deacetylase Complexes Promote Trinucleotide Repeat Expansions
PLoS Biol 10(2): e1001257. doi:10.1371/journal.pbio.1001257
Kim Debacker#, Aisling Frizzell#, Olive Gleeson, Lucy Kirkham-McCarthy, Tony Mertz, Robert S. Lahue*
Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland
OPEN ACCESS
Currently some researchers and pharmaceutical labs are testing HDACi for relief of the transcription-related consequences of expansions in triplet expansion diseases, they may also have the beneficial side effect of reducing the risk of further somatic expansion.
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Kim Debacker#, Aisling Frizzell#, Olive Gleeson, Lucy Kirkham-McCarthy, Tony Mertz, Robert S. Lahue*
Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland
OPEN ACCESS
Currently some researchers and pharmaceutical labs are testing HDACi for relief of the transcription-related consequences of expansions in triplet expansion diseases, they may also have the beneficial side effect of reducing the risk of further somatic expansion.
Full text pdf
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