Wednesday, February 29, 2012

Modelling Friedreich's Ataxia Using Human Induced Pluripotent Stem Cells

The Scripps Research Institute Graduate Program. Thesis for the degree of Doctor of Philosophy in the subject of Biology.La Jolla,California March 2011.

Sherman Ku

Keywords: Friedreich’s ataxia (FRDA), GAA•TTC triplet repeat expansion, heterochromatin-mediated compaction, frataxin gene, induced pluripotent stemcells (iPSCs), fibroblasts, MSH2.

MOLECULAR DETAILS OF THE PROTEINS INVOLVED MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY

Wayne State University Theses. Paper 148. (2011)

YOGAPRIYA MURUGESAN

Keywords: Friedrich's ataxia, frataxin, Fe-S cluster assembly, reactive oxygen species, cysteine desulfurase Nfs1, scaffold protein Isu, metal iron.