DNA Mismatch Repair Complex MutSβ Promotes GAA·TTC Repeat Expansion ; Anasheh Halabi, Scott Ditch, Jeffrey Wang, and Ed Grabczyk; J. Biol. Chem. 2012 287: 29958-29967. First Published on July 11, 2012, doi:10.1074/jbc.M112.356758
Keywords: DNA repair, CAG·CTG repeat expansion, Friedreich ataxia (FRDA), human cellular model, expansion rate, DNA repair enzymes, MutSβ, MSH2, MSH3, FXN gene. therapeutic target.
Friday, August 24, 2012
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