The Case for Induced Pluripotent Stem Cell-derived Cardiomyocytes in Pharmacological Screening

The Case for Induced Pluripotent Stem Cell-derived Cardiomyocytes in Pharmacological Screening.Jaffar M Khan, Alexander R. Lyon and Sian E. Harding; British Journal of Pharmacology. Accepted manuscript online: 27 JUL 2012 DOI: 10.1111/j.1476-5381.2012.02118.x

Keywords: cardiac, stem cell, embryonic, iPSC, safety, cardiotoxicity, high throughput, drug screening models, human cardiomyocytes, pharmacology.

The Spectrum of Left Ventricular Changes in Friedreich Ataxia—Relation to Age and GAA Repeats in the Frataxin Gene

The Spectrum of Left Ventricular Changes in Friedreich Ataxia—Relation to Age and GAA Repeats in the Frataxin Gene. G. Romanelli, M. Delatycki, L. Donelan, R. Hassam, L. Corben, R. Peverill. Heart, Lung and Circulation, Volume 21, Supplement 1, 2012, Pages S273 DOI: http://dx.doi.org/10.1016/j.hlc.2012.05.668

Keywords: Increased LV RWT, GAA1, LV size, wall thickness or mass, age.

Echocardiographic Parameters in the Assessment of Friedreich's Ataxia with Preserved Left Ventricular Systolic Function

Echocardiographic Parameters in the Assessment of Friedreich's Ataxia with Preserved Left Ventricular Systolic Function. L. Eng, D. Duncan, I. Cukovski, L. Jijnasu, K. Davies, P. Palka. Heart, Lung and Circulation Volume 21, Supplement 1, 2012, Pages S201–S202. http://dx.doi.org/10.1016/j.hlc.2012.05.499.

Keyword: Friedreich's ataxia (FRDA), cardiac dysfunction, ,FRDA cardiomyopathy, left ventricular hypertrophy, diastolic dysfunction, myocardial dysfunction, echocardiographic, cardiac dimensions, Doppler imaging (TDI).