Wednesday, April 27, 2016

Genome Engineering with TALE and CRISPR Systems in Neuroscience

Han B. Lee, Brynn N. Sundberg, Ashley N. Sigafoos, and Karl J. Clark. Front Genet. 2016; 7: 47. doi: 10.3389/fgene.2016.00047

OPEN ACCESS

These technologies mirror and extend beyond classic gene targeting methods contributing to the development of novel tools for basic and clinical neuroscience. In this Review, we discuss the recent development in genome engineering and potential applications of this technology in the field of neuroscience.