ClinicalTrials.gov Identifier: NCT03120013 First received: April 14, 2017
Neurodegenerative cerebellar ataxias represent a group of disabling disorders for which we currently lack effective therapies. Cerebellar transcranial direct current stimulation (tDCS) is a non-invasive technique, which has been demonstrated to modulate cerebellar excitability and improve symptoms in patients with cerebellar ataxias. In this randomized, double-blind, sham-controlled study, the investigators will evaluate whether a two-weeks' treatment with cerebellar anodal tDCS and spinal cathodal tDCS can improve symptoms in patients with neurodegenerative cerebellar ataxia and can modulate cerebello-motor connectivity, at short and long term.
Condition:
Ataxia, Cerebellar, Cerebellar Ataxia, Spinocerebellar Ataxias, Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia 3, Spinocerebellar Degenerations, Friedreich Ataxia, Ataxia With Oculomotor Apraxia, Multiple System Atrophy.
Intervention:
Device: Anodal cerebellar and cathodal spinal tDCS, Device: Sham cerebellar and sham spinal tDCS.
Locations:
Italy, AO Spedali Civili, Brescia, BS, Italy, 25100
Contact: Barbara Borroni
Thursday, April 20, 2017
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