We revealed the therapeutic potential of SF and how it performs in comparison with omaveloxolone and DMF, in a physiologically and genetically relevant in vitro FRDA model. Conclusion: SF offers a multipronged approach to alleviating the different cellular events underlying FRDA.
Sunday, June 15, 2025
Sulforaphane Targets Multiple Pathological Processes in Friedreich Ataxia Patient-Induced Pluripotent Stem Cell-Derived Sensory Neurons
Yang W, Thompson B, Miellet S, Maddock M, Napierala M, Dottori M, Kwa F. Sulforaphane Targets Multiple Pathological Processes in Friedreich Ataxia Patient-Induced Pluripotent Stem Cell-Derived Sensory Neurons. Antioxid Redox Signal. 2025 May 23. doi: 10.1089/ars.2024.0756. Epub ahead of print. PMID: 40406806.
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