Epidemiology of Hereditary Ataxias in Spain: Hospital Discharge Registry and Population-Based Mortality Study

Epidemiology of Hereditary Ataxias in Spain: Hospital Discharge Registry and Population-Based Mortality Study. Alonso V., Villaverde-Hueso A., Hens M.J., Morales-Piga A., Abaitua I., Posada de la Paz M.; Neuroepidemiology 2013;41:13-19 (DOI:10.1159/000346275).

Keywords: Hereditary ataxias (HA), genetically heterogeneous rare diseases, morbimortality of HA, national death index (1981-2008), Friedreich's ataxia (45.4%), non-Friedreich group(54.6%).

Discovery of a Novel Small Molecule Inhibitor Targeting the Frataxin/Ubiquitin Interaction via Structure-Based Virtual Screening and

Discovery of a Novel Small Molecule Inhibitor Targeting the Frataxin/Ubiquitin Interaction via Structure-Based Virtual Screening and. Antonio Lavecchia, Carmen Di Giovanni, Carmen Cerchia, Annapina Russo, Giulia Russo, Ettore Novellino; J. Med. Chem., Just Accepted Manuscript. DOI: 10.1021/jm3017199

Keywords: Friedreich ataxia (FRDA), frataxin, ubiquitin–proteasomal pathway, residue K147, potential ubiquitin-binding domain.