Thursday, July 21, 2011

Rim2, pyrimidine nucleotide exchanger, is needed for iron utilization in mitochondria

Biochem. J. (2011) Immediate Publication, doi:10.1042/BJ20111036

Heeyong Yoon, Yan Zhang, Jayashree Pain, Elise R. Lyver, Emmanuel Lesuisse, Debkumar Pain and Andrew Dancis
University of Pennsylvania, Philadelphia, U.S.A

Keywords: Mitochondria, iron, heme, Fe-S clusters, Mrs3, Mrs4, Yfh1, frataxin homolog, Rim2, mitochondrial carrier protein, pyrimidine exchange, promoting mitochondrial iron utilization.

Cardiac Dysfunction Causes Majority of Deaths in Friedreich's Ataxia

Original paper: Mortality in friedreich ataxia.

By: SHARON WORCESTER, Internal Medicine News Digital Network

Cardiac dysfunction remains the most common cause of death in patients with Friedreich’s ataxia, according to the findings of a retrospective study. read more