Keywords: Friedreich ataxia, neurodegenerative disease, frataxin, iron sulfur cluster (ISC), cellular iron dysregulation, potential novel therapeutic approaches.
Monday, April 26, 2010
Understanding the molecular mechanisms of Friedreich Ataxia to develop therapeutic approaches.
Hum Mol Genet. 2010 Apr 22.
Stéphane Schmuckera,d,e and Hélène Puccioa,b,c,d,e,* a IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), 1 rue Laurent Fries, BP10142, Illkirch, F-67400 France ; b Inserm, U596, Illkirch, F-67400 France ; c CNRS, UMR7104, Illkirch, F-67400 France ; d Université Louis Pasteur, Strasbourg, F-67000, France ; e Collège de France, Chaire de génétique humaine, Illkirch, F-67400 France
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