Una “ambulancia” para el cerebro. IRB Barcelona Scientic News
Junto a investigadores clínicos, están preparando terapias para el glioblastoma –el cáncer cerebral más agresivo en adultos-, la Ataxia de Friedreich –una enfermedad neurodegenerativa hereditaria- y próximamente para un tipo de cáncer cerebral infantil.
Friday, February 6, 2015
An “ambulance” for the brain
An “ambulance” for the brain. IRB Barcelona Scientific News
Together with clinical researchers, they are preparing treatments for glioblastoma—the most aggressive brain cancer in adults—, Friedreich’s Ataxia—a hereditary neurodegenerative disease—, and a type of paediatric brain cancer
Together with clinical researchers, they are preparing treatments for glioblastoma—the most aggressive brain cancer in adults—, Friedreich’s Ataxia—a hereditary neurodegenerative disease—, and a type of paediatric brain cancer
Applying the Retro-Enantio Approach to Obtain a Peptide Capable of Overcoming the Blood–Brain Barrier
Applying the Retro-Enantio Approach to Obtain a Peptide Capable of Overcoming the Blood–Brain Barrier. Dr. Roger Prades, Benjamí Oller-Salvia, Dr. Susanne M. Schwarzmaier, Dr. Javier Selva, Dr. María Moros, Matilde Balbi, Dr. Valeria Grazú, Dr. Jesus M. de La Fuente, Prof. Gustavo Egea, Prof. Nikolaus Plesnila, Dr. Meritxell Teixidó and Prof. Ernest Giralt; Angewandte Chemie Intl Edition (February 2015) DOI: 10.1002/anie.201411408
"In conclusion, we report a protease-resistant peptide with the capacity to transport cargos of distinct sizes and types across the BBB, one of the most restrictive barriers in the human body.
This potential BBB shuttle brings with it the possibility to fulfil an unmet clinical need, namely the treatment of CNS disorders."
"In conclusion, we report a protease-resistant peptide with the capacity to transport cargos of distinct sizes and types across the BBB, one of the most restrictive barriers in the human body.
This potential BBB shuttle brings with it the possibility to fulfil an unmet clinical need, namely the treatment of CNS disorders."
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