We report that the IR significantly improves motor performance and ataxia symptoms in patients with FRDA. Our study shows significant functional improvement in all the outcome measures used, except for NHPT bilaterally. FARS and SARA scores post-IR are significatively reduced when compared (p < 0.001).
Wednesday, November 15, 2023
Effectiveness of rehabilitation intervention in persons with Friedreich ataxia
Paparella G, Stragà C, Vavla M, Pesenti N, Merotto V, Martorel GA, Zalunardo S, Armellin M, Comiotto J and Martinuzzi A (2023) Effectiveness of rehabilitation intervention in persons with Friedreich ataxia. Front. Neurol. 14:1270296. doi: 10.3389/fneur.2023.1270296
The Cardiac Calcium Handling Machinery is Remodeled in Friedreich's Ataxia
The Cardiac Calcium Handling Machinery is Remodeled in Friedreich's Ataxia, Roman Czornobil, Obada Abou- Assali, Elizabeth Remily- Wood, David R Lynch, Sami F. Noujaim, Bojjibabu Chidipi
bioRxiv 2023.11.09.566141; doi:10.1101/2023.11.09.566141
Conclusion: The development of left ventricular contractile dysfunction in FA is associated with reduced expression of calcium handling proteins and mitochondrial dysfunction.
Subscribe to:
Posts (Atom)
