Wednesday, October 17, 2018

Developmental and Neurodegenerative Damage in Friedreich Ataxia

Rezende TJR, Martinez ARM, Faber I, Girotto K, Martins MP, de Lima FD, Lopes-Cendes I, Cendes F, França MC; Eur J Neurol. Accepted Author Manuscript. . doi:10.1111/ene.13843

Structural damage in FRDA begins in spinal cord, inferior cerebellar peduncle as well as red nucleus, and progresses to cerebral areas in adulthood. These results shed some light in the early FRDA stages and highlight potential neuroimaging markers for therapeutic trials.