Sunday, June 24, 2018

Frataxin‐Mediated PINK1‐Parkin‐Dependent Mitophagy in Hepatic Steatosis: The Protective Effects of Quercetin

Liu, P. , Lin, H. , Xu, Y. , Zhou, F. , Wang, J. , Liu, J. , Zhu, X. , Guo, X. , Tang, Y. and Yao, P. (2018), Mol. Nutr. Food Res.. Accepted Author Manuscript. . doi:10.1002/mnfr.201800164

Naturally occurring quercetin has been found to induce mitophagy and prevent non‐alcoholic fatty liver disease (NAFLD). However, it still remains elusive whether frataxin upregulation by quercetin contributes to the beneficial effect through mitophagy or not.