Qureshi, M. Y., Patterson, M. C., Clark, V., Johnson, J. N., Moutvic, M. A., Driscoll, S. W., Kemppainen, J. L., Huston, J., 3rd, Anderson, J. R., Badley, A. D., Tebben, P. J., Wackel, P., Oglesbee, D., Glockner, J., Schreiner, G., Dugar, S., Touchette, J. C., & Gavrilova, R. H. (2020). Journal of inherited metabolic disease, 10.1002/jimd.12285. Advance online publication. doi:10.1002/jimd.12285
(+)-EPI was well tolerated over 24 weeks at up to 150 mg/day. Improvement was observed in cardiac structure and function in subset of subjects with FRDA without statistically significant improvement in primary neurological outcomes.
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