Monday, November 9, 2009

Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone

Nature Neuroscience

Published online: 8 November 2009
doi:10.1038/nn.2437
Celia Andreu-Agulló, José Manuel Morante-Redolat, Ana C Delgado & Isabel Fariñas.
About stem cells, neurodegeneration, not specific Friedreich ataxia
Keywords: stem cell microenvironments, regulate self-renewal,  astroglia-like neural stem cells (NSCs), Notch transcriptional activity,  multipotency, Pigment epithelium–derived factor (PEDF), NF-B pathway, N-CoR.
 
Link To Full text: http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.2437.html