Saturday, December 18, 2010

Iron-dependent functions of mitochondria-relation to neurodegeneration.

J Neural Transm. 2010 Dec 15.
Gille G, Reichmann H.
Klinik und Poliklinik für Neurologie, TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany

Keywords: neurodegenerative diseases, iron dyshomeostasis, mitochondrial dysfunction, physiological role of iron in mitochondria, Friedreich ataxia (FRDA),idiopathic Parkinson disease (PD), respiratory chain, iron-sulphur clusters, cytochromes, aconitase, frataxin gene, frataxin, reactive oxygen species.