BMC Systems Biology 2011, 5:6doi:10.1186/1752-0509-5-6
Shiek S.S.J Ahmed, Abdul R. Ahameethunisa, Winkins Santosh, Srinivasa Chakravarthy and Suresh Kumar
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This study improves the understanding of the complex interactions that occur between neurological and psychiatric diseases with aging, which lead to determine the diagnostic markers. Also, the disease-disease association results could be helpful to determine the symptom relationships between neurological and psychiatric diseases. Together, our study presents many research opportunities in post-genomic biomarker development.
"this approach provides the additional information that PDHB is not only associated with Parkinson’s disease but also associated with Athetosis and Friedreich Ataxia"
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Tuesday, January 18, 2011
Information from cochlear potentials and genetic mutations helps localize the lesion site in auditory neuropathy
Genome Med 2010, 2:91 doi:10.1186/gm212
Rosamaria Santarelli, Department of Medical and Surgical Specialities, Service of Audiology and Phoniatrics, University of Padua
Keywords: Auditory neuropathy (AN), disruption of auditory nerve activity, impairment of speech perception, hearing loss, abnormality of auditory brainstem potentials, preserved outer hair-cell activities, multisystem involvement, peripheral and optic neuropathies, abnormal cochlear potentials have been recorded from patients, genetically based auditory neuropathies, molecular mechanisms.
Rosamaria Santarelli, Department of Medical and Surgical Specialities, Service of Audiology and Phoniatrics, University of Padua
Keywords: Auditory neuropathy (AN), disruption of auditory nerve activity, impairment of speech perception, hearing loss, abnormality of auditory brainstem potentials, preserved outer hair-cell activities, multisystem involvement, peripheral and optic neuropathies, abnormal cochlear potentials have been recorded from patients, genetically based auditory neuropathies, molecular mechanisms.
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