Cell Death and Disease (2011) 2, e123; doi:10.1038/cddis.2011.5
Guccini I, Serio D, Condò I, Rufini A, Tomassini B, Mangiola A, Maira G, Anile C, Fina D, Pallone F, Mongiardi MP, Levi A, Ventura N, Testi R, Malisan F
Keywords: frataxin, Friedreich's ataxia, oxidative stress, apoptosis, tumor suppressor, stress resistance, tumor cells, response to hypoxic stress, hypoxia-inducible factors (HIF), tumor-suppressor p53.
"frataxin is in fact increased in human tumors in vivo"
"Frataxin upregulation in response to hypoxia is dependent on hypoxia-inducible factors expression"
Friday, March 4, 2011
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