Wednesday, March 9, 2022

The Cognitive Profile of Friedreich Ataxia: A Systemic Review and Meta-Analysis

Naeije g, Schul JB, Corben L.; Research Square; 2022. DOI: 10.21203/rs.3.rs-1010466/v1. 

Individuals with FRDA display significantly lower performances in many cognitive domains compared to control participants. The spectrum of the cognitive profile alterations in FRDA and its correlation with disease severity and cerebellar structural parameters suggest a cerebellar role in the pathophysiology of FRDA cognitive impairments. (Preprint)


Naeije G, Schulz JB, Corben LA. The cognitive profile of Friedreich ataxia: a systematic review and meta-analysis. BMC Neurol. 2022 Mar 17;22(1):97. doi: 10.1186/s12883-022-02615-3. PMID: 35300598.