This paper aims to provide a concise and objective review of the oxidative and antioxidant pathways and their potential therapeutic applications in treating oxidative injury in the brain.
Sunday, November 24, 2024
Safeguarding the brain from oxidative damage
Kyung Hee Lee, Un Jeng Kim, Bae Hwan Lee, Myeounghoon Cha, Safeguarding the brain from oxidative damage, Free Radical Biology and Medicine, Volume 226, 2025, Pages 143-157, ISSN 0891-5849, doi:10.1016/j.freeradbiomed.2024.11.019.
Exploring neuropsychiatric symptoms in Friedreich ataxia
Karamazovova, S., Stovickova, L., Jester, D.J. et al. Exploring neuropsychiatric symptoms in Friedreich ataxia. Sci Rep 14, 29076 (2024). doi:10.1038/s41598-024-80258-9
In conclusion, our findings show that NPS are common in FRDA and manifest not only as depression and anxiety but also as decreased motivation. It is difficult to distinguish whether these NPS are due to the neurodegenerative process or to the burden of living with a progressive, devastating disease, but in any case they need to be considered in clinical care.
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