An Optimized Pyrimidinol Multifunctional Radical Quencher

An Optimized Pyrimidinol Multifunctional Radical Quencher. Omar M. Khdour , Pablo M. Arce , Basab Roy , and Sidney M. Hecht; ACS Med. Chem. Lett., Just Accepted Manuscript, DOI: 10.1021/ml400130z, Publication Date (Web): May 28, 2013

Keywords: aza analogues (4-9) of idebenone, to attenuate oxidative stress, Friedreich’s ataxia (FRDA), mitochondrial and neurodegenerative diseases, FRDA, Alzheimer's disease.

Facile Electrochemical Biosensor Based on a New Bifunctional Probe for Label-Free Detection of CGG Trinucleotide Repeat

Facile Electrochemical Biosensor Based on a New Bifunctional Probe for Label-Free Detection of CGG Trinucleotide Repeat. Hanping He, Jingping Xia, Xiaoqian Peng, Gang Chang, Xiuhua Zhang, Yafen Wang, Kazuhiko Nakatani, Zhaowen Lou, Shengfu Wang. Biosensors and Bioelectronics, Available online 28 May 2013, http://dx.doi.org/10.1016/j.bios.2013.05.022

The strategy should have significant potential for the development of versatile and low-cost biosensor for early diagnosis and treatment of neurodegenerative diseases associated with trinucleotide repeats.

Keywords: Electrochemical biosensor, Trinucleotide repeat, Ferrocenyl modified naphthyridine derivative,

A NEURONAL MODEL OF NEURODEGENERATIVE DISEASE: OXIDATIVE STRESS IN THE AXONAL DAMAGE.

A NEURONAL MODEL OF NEURODEGENERATIVE DISEASE: OXIDATIVE STRESS IN THE AXONAL DAMAGE. Emanuela Piermarini, Barbara Carletti, Giulia Tozzi, Lorena Travaglini, Anna Pastore, Alessandra Torraco, Enrico Bertini and Fiorella Piemonte. RIUNIONI SCIENTIFICHE SULLA RICERCA BIOMEDICA DELL’OSPEDALE PEDIATRICO BAMBINO GESU’ E DELL’UNIVERSITA’ ROMA TRE
Martedì 28 Maggio 2013 “Stress ossidativo e patologie correlate”

Keywords: Neurons, oxidative stress, axonal damage, neuronal cell models, Friedreich’s Ataxia (FRDA), ate this neuronal cell model, shRNA lentiviral vector, axonal pathological profile of FRDA, reduced glutathione.