Movement Disorders, Early View (Articles online in advance of print),Published Online: 11 Dec 2009
Arunjot Singh, MS, Elizabeth Epstein, BA, Lauren M. Myers, BA, Jennifer M. Farmer, MS, David R. Lynch, MD, PhD
Departments of Neurology and Pediatrics, University of Pennsylvania School of Medicine and The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Keywords: ataxia, sensory neuron, dysarthria, balance, clinical trial, Friedreich Ataxia (FA), speech, therapeutic monitoring.
Sunday, December 13, 2009
AF4 Is a Critical Regulator of the IGF-1 Signaling Pathway during Purkinje Cell Development
The Journal of Neuroscience, December 9, 2009, 29(49):15366-15374; doi:10.1523/JNEUROSCI.5188-09.2009
Emmanuelle Bitoun,1,2 * Mattéa J. Finelli,1,2 * Peter L. Oliver,1,2 Sheena Lee,1 and Kay E. Davies1,2
1Medical Research Council Functional Genomics Unit, and 2Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, United Kingdom
Keywords: insulin-like growth factor 1 (IGF-1), cerebellar ataxia, neuronal cell death, targeted for therapy, Purkinje cell (PC) death, cerebellum, transcriptional cofactor.
1Medical Research Council Functional Genomics Unit, and 2Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, United Kingdom
Keywords: insulin-like growth factor 1 (IGF-1), cerebellar ataxia, neuronal cell death, targeted for therapy, Purkinje cell (PC) death, cerebellum, transcriptional cofactor.
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