Nishaki Mehta, Paul Chacko, James Jin, Tam Tran, Thomas W. Prior, Xin He, Gunjan Agarwal, and Subha V. Raman (2016). Texas Heart Institute Journal: August 2016, Vol. 43, No. 4, pp. 305-310.
doi:10.14503/THIJ-14-4198
We conclude that PICP, a serum marker of collagen synthesis, is elevated in Friedreich ataxia and indicates baseline abnormal LV geometry and subsequent dilation. Cardiac magnetic resonance and PICP warrant consideration as complementary biomarkers in therapeutic trials of Friedreich ataxia cardiomyopathy.
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