Oxidative Stress Studies in Yeast With a Frataxin Mutant; A Proteomics Perspective

Proteome Res., Just Accepted Manuscript

Publication Date (Web): December 3, 2009

 

Jin-Hee Kim , Miroslav Sedlak , Qiang Gao , Catherine P Riley , Fred Regnier and Jiri Adamec

 

Department of Chemistry, Laboratory of Renewable Resources Engineering, Department of Agricultural and Biological Engineering, Bindley Bioscience Center at Discovery Park, Purdue University, West Lafayette, IN USA 47907

Keywords: Cellular response, Δyfh1 mutant, oxidative stress, iron, mitochondria,  carbonyl groups, reactive oxygen species (ROS), proteomic techniques, protein carbonylation.

 

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Absence of aprataxin gene mutations in a Greek cohort with sporadic early onset ataxia and normal GAA triplets in frataxin gene.

Neurol Sci. 2009 Dec 2.

Daiou C, Christodoulou K, Xiromerisiou G, Panas M, Dardiotis E, Kladi A, Speletas M, Ntaios G, Papadimitriou A, Germenis A, Hadjigeorgiou GM.

Laboratory of Neurogenetics, Neuroscience Unit, Department of Neurology, Faculty of Medicine, University of Thessalia, Larissa, Greece.

Keywords: Phenotype, aprataxin gene mutation,  GAA expansion,  frataxin gene, exons, flanking intronic sequences, cerebellar ataxia, point mutation, Friedreich ataxia.

A neurite quality index and machine vision software for improved quantification of neurodegeneration

BioTechniques, Vol. 47, No. 6, December 2009, pp. iii–viii

Peggy L. Romero1, Ted Miller2, and Arman M. Garakani2
1Sirtris, A GSK Company, Cambridge, MA, USA
2Reify Corporation, Saratoga, CA, USA
 
Keywords: neurodegradation in dorsal root ganglion cultures,  model for neurodegenerative diseases, quantify neuroprotection, neurite quality index (NQI),  neurosight,  vision-based method, SIRT1, resveratrol, nicotinamide adenine dinucleotide (NAD), axons.
 
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