Tuesday, April 13, 2010

Analysis of the factors influencing the cardiac phenotype in Friedreich's ataxia

Movement Disorders, Volume 9999, Issue 9999 , PagesNA - (Published Online: 13 Apr 2010)

Bheeshma Rajagopalan, FRCP 1, Jane M. Francis, DCR(R) 2, Fraser Cooke, MRCP 1, L. V. Prasad Korlipara, MRCP 3, Andrew M. Blamire, PhD 1, Anthony H.V. Schapira, FMedSci 3, Jason Madan, MSc 4, Stefan Neubauer, FRCP 2, J. Mark Cooper, PhD 3 *1Nuffield Department of Medicine, Department of Biochemistry, University of Oxford, Oxford, UK
2University of Oxford Centre for Clinical Magnetic Resonance Research, Oxford, UK
3Clinical Neurosciences, Institute of Neurology, UCL, London, UK
4Health Economics and Decision Science, ScHARR, University of Sheffield, Sheffield, UK

Funded by: Ataxia UK and the Medical Research Council

Keywords: Friedreich's ataxia (FRDA), cardiac hypertrophy, dilated cardiomyopathy, magnetic resonance imaging (MRI), LV mass, genetic mutation, GAA repeats, age of onset, effect of treatment.