Tuesday, March 23, 2010

Evidence that yeast frataxin is not an iron storage protein In Vivo

Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseArticle in Press, Accepted Manuscript, doi:10.1016/j.bbadis.2010.03.008

Alexandra Seguina, 1, Robert Sutaka, 1, Anne-Laure-Bulteaub, Richard Garcia-Serresc, Jean-Louis Oddouc, Sophie Lefevrea, Renata Santosa, Andrew Dancisd, Jean-Michel Camadroa, Jean-Marc Latourc, 2 and Emmanuel Lesuissea, 2, Corresponding Author Contact Information, E-mail The Corresponding Author


a Laboratoire Mitochondries, Métaux et Stress oxydant, Institut Jacques Monod, CNRS-Université Paris Diderot, France.
b Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris 7, Paris, France.
c CEA, iRTSV, LCBM, 38054 Grenoble Cedex 9, France; CNRS, UMR5249, Grenoble, France; Université Joseph Fourier, 38054 Grenoble Cedex 9, France
d University of Pennsylvania, Department of Medicine, Division of Hematology/Oncology, BRBII Room 731, 431 Curie Blvd, Philadelphia PA 19104, USA
Received 10 October 2009; 
revised 14 March 2010; 
accepted 16 March 2010. 
Available online 20 March 2010.


Keyword:  Yeast frataxin; iron; oxidative stress; yfh1; ggc1; Mössbauer; mitochondria