Friday, March 12, 2010

Does oxidative stress contribute to the pathology of Friedreich's ataxia? A radical question.

FASEB J. 2010 Mar 10.

Armstrong JS, Khdour O, Hecht SM.
Center for BioEnergetics, Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

Keywords: Friedreich's ataxia (FRDA, neurodegenerative disease, frataxin, mitochondrial iron accumulation, Fenton-mediated free radical production, reactive oxygen species (ROS), specific small molecule multifunctional antioxidants.