Wednesday, March 31, 2010

North and South Indian Populations Share a Common Ancestral Origin of Friedreich's Ataxia but Vary in Age of GAA Repeat Expansion

Annals of Human Genetics, Early View (Articles online in advance of print)
Published Online: 31 Mar 2010

Inder Singh 1# , Mohammed Faruq 1,2# , Odity Mukherjee 3 , Sanjeev Jain 4 , Pramod Kumar Pal 4 , M. V. Padma Srivastav 1 , Madhuri Behari 1 , Achal K. Srivastava 1 and Mitali Mukerji 2*
1 Neuroscience Centre, All India Institute of Medical Sciences, New Delhi, India 2 Genomics and Molecular Medicine, Institute of Genomics and Integrative Biology, (IGIB) CSIR, Mall Road, New Delhi, India 3 National Centre for Biological Sciences, Bangalore, India 4 National Institute of Mental Health and Neuro Sciences, Bangalore, India

KEYWORDS: Age of mutation • CS2 • founder haplotype • FAD1 • FRDA • FR6 • FRDA India • GAA repeats • ITR3