Modelling Friedreich's Ataxia Using Human Induced Pluripotent Stem Cells

The Scripps Research Institute Graduate Program. Thesis for the degree of Doctor of Philosophy in the subject of Biology.La Jolla,California March 2011.

Sherman Ku

Keywords: Friedreich’s ataxia (FRDA), GAA•TTC triplet repeat expansion, heterochromatin-mediated compaction, frataxin gene, induced pluripotent stemcells (iPSCs), fibroblasts, MSH2.