Saturday, April 13, 2013

The L-Cysteine Desulfurase NFS1 Is Localized in the Cytosol where it Provides the Sulfur for Molybdenum Cofactor Biosynthesis in Humans

The L-Cysteine Desulfurase NFS1 Is Localized in the Cytosol where it Provides the Sulfur for Molybdenum Cofactor Biosynthesis in Humans,Zvonimir Marelja, Mita Mullick Chowdhury, Carsten Dosche, Carsten Hille, Otto Baumann, Hans-Gerd Löhmannsröben, Silke Leimkühler; PLoS ONE 8(4): e60869. doi:10.1371/journal.pone.0060869

Fifth Congress of the International BioIron Society (IBIS) (BioIron 2013) at University College London.

Fifth Congress of the International BioIron Society (IBIS) (BioIron 2013) at
University College London. 2013 Program Book - International BioIron Society, April 14-18

Podium #36
IRP-1 CONTROLS IRON METABOLISM IN FRATAXIN-DEFICIENT TISSUES
Alain Martelli, PhD, Stéphane Schmucker, PhD, Laurence Reutenauer, Hervé Puy, Prof., Bruno Galy, PhD, Matthias
Hentze, Prof. and Hélène Puccio, Research Director

Podium #47
ABNORMAL BODY IRON DISTRIBUTION AND ERYTHROPOIESIS IN A NOVEL MOUSE MODEL WITH INDUCIBLE GAIN
OF IRON REGULATORY PROTEIN (IRP) -1 FUNCTION

Daniela Casarrubea, MSc, Lydie Viatte, PhD, Tina Hallas, Aparna Vasanthakumar, PhD, Richard S. Eisenstein, PhD, Klaus
Schümann, PhD, Matthias W. Hentze, PhD and Bruno Galy, PhD

Podium #66
IDENTIFICATION OF NONFERRITIN MITOCHONDRIAL IRON DEPOSITS IN A MOUSE MODEL OF FRIEDREICH ATAXIA
Des R. Richardson, M. Whitnall, Y. Suryo Rahmant, M.L.H. Huang, F. Saletta, H.C. Lok, L. Gutierrez, F.J. Lazaro, A.J.
Fleming, T.G. St Pierre, M.R. Mikhael and P. Ponka

Poster #34
MITOCHONDRIAL PROTEIN, FRATAXIN, IS DOWNREGULATED IN HEMODIALYSIS PATIENTS
Takeshi Nakanishi, MD, PhD; Yukiko Hasuike, MD,PhD; Soshi Yorifuji, MD; Ayako Matsumoto, MD; Mana Yahiro, MD, PhD;
Aritoshi Kida, MD; Yasuyuki Nagasawa, MD, PhD; Takahiro Kuragano, MD, PhD

Poster #35
FRATAXIN IS A REGULATOR OF THE FE-S BIOGENESIS
Salvatore Adinolfi, biologist

Poster #39
MITOCHONDRIA-TARGETED IRON CHELATORS FOR THE MONITORING AND ADJUSTMENT OF CELLULAR LABILE
IRON POOLS

Vincenzo Abbate, PhD; Robert Hider, PhD; Charareh Pourzand, PhD; Olivier Reelfs, PhD

Poster #62
DOWN REGULATION OF RESPIRATORY ENZYMES IN FRATAXIN DEFICIENT YEAST IS MEDIATED BY THE
METABOLIC REGULATORS ADR1 AND CTH2

David Alsina, Armando Moreno-Cermeño, Elia Obis, Joaquim Ros and Jordi Tamarit

Poster #64
DEFINING THE ARCHITECTURE OF THE MITOCHODRIAL IRON-SULFUR CLUSTER ASSEMBLY MACHINERY
Belinda Galean

Poster #214
A CELL MODEL FOR FRIEDREICH ATAXIA USING DORSAL ROOT GANGLIA NEURONS
Stefka Mincheva-Tasheva, PhD, Elia Obis, Joaquim Ros, PhD and Jordi Tamarit, PhD

Poster #231
NOVEL LIGHT-ACTIVATED CAGED IRON CHELATORS: TARGETED PRODRUGS FOR IRON RELATED-DISORDERS
Benjamin Young, MPharm, Olivier Reelfs, PhD, DSc, Asma Aroun, PhD, Seyed Ali Miri, BSc, Magnus Hoffmann, BSc,
Charareh Pourzand, PhD, DSc and Ian Eggleston

Poster #273
A PRIMARY CULTURE OF CARDIOMYOCYTES WITH FRATAXIN DEFICIENCY EXHIBITS A METABOLIC SWITCH
BEFORE IRON DISARRANGEMENTS

Elia Obis, David Alsina, Joaquim Ros and Jordi Tamarit



Therapeutic Strategies in Friedreich's Ataxia

Therapeutic Strategies in Friedreich's Ataxia. Timothy E. Richardson, Heather N. Kelly, Amanda E. Yu, James W. Simpkins; Brain Research, Available online 13 April 2013. http://dx.doi.org/10.1016/j.brainres.2013.04.005

Keywords: Friedreich's ataxia (FA), FXN, frataxin, therapeutic research, ongoing treatment strategies, 17β-estradiol, methylene blue.