Wednesday, May 4, 2016

Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation

Arnulf H. Koeppen, R. Liane Ramirez, Alyssa B. Becker and Joseph E. Mazurkiewicz. Acta Neuropathologica Communications, Neuroscience of Disease 20164:46 DOI: 10.1186/s40478-016-0288-5

We conclude that FA differentially affects the key cellular elements of DRG, and postulate that the disease causes loss of bidirectional trophic support between satellite cells and neurons.