Thursday, June 28, 2012

A0001 in Friedreich ataxia: Biochemical characterization and effects in a clinical trial

A0001 in Friedreich ataxia: Biochemical characterization and effects in a clinical trial. Lynch, D. R., Willi, S. M., Wilson, R. B., Cotticelli, M. G., Brigatti, K. W., Deutsch, E. C., Kucheruk, O., Shrader, W., Rioux, P., Miller, G., Hawi, A. and Sciascia, T. Mov. Disord.. doi: 10.1002/mds.25058.

Keywords: A0001 (α-tocopheryl quinone; EPI-A0001), potent antioxidant, in vitro measures, glucose metabolism, neurological function, Friedreich ataxia, in vitro study, double-blind, randomized, placebo-controlled trial, disposition Index, diabetic tendency, glucose tolerance test, Friedreich Ataxia Rating Scale.