In Epigenomics, Location Is Everything: Researchers Exploit Gene Position to Test 'Histone Code'

In Epigenomics, Location Is Everything: Researchers Exploit Gene Position to Test 'Histone Code'. Menzies Chen, Katherine Licon, Rei Otsuka, Lorraine Pillussend, Trey Idekersend. Cell Reports, 03 January 2013

Also: Science News, Jan. 3, 2013,
Jan. 3, 2013 — In a novel use of gene knockout technology, researchers at the University of California, San Diego School of Medicine tested the same gene inserted into 90 different locations in a yeast chromosome -- and discovered that while the inserted gene never altered its surrounding chromatin landscape, differences in that immediate landscape measurably affected gene activity.