A Novel Mouse Model for Friedreich's Ataxia

A Novel Mouse Model for Friedreich's Ataxia. Inventors: Geschwind, Daniel H.; UCLA Office of Intellectual Property & Industry Sponsored Research

This new model exhibits various symptoms observed in FRDA patients, including cardiac atrophy, elevated iron-responsive proteins, neurodegeneration, motor neuropathy–and for the first time in an FRDA model–scoliosis and ataxia.