Unexpected nerve neuroimaging findings in Friedreich’s ataxia

Unexpected nerve neuroimaging findings in Friedreich’s ataxia. Alessandro Salvalaggio, Mario Cacciavillani, Marta Lucchetta, Renzo Manara, Roberto Gasparotti, Chiara Briani; Clinical Neurophysiology, Available online 8 September 2014, ISSN 1388-2457, http://dx.doi.org/10.1016/j.clinph.2014.08.014.

Our findings may support a myelin involvement in the pathogenic mechanism of the FRDA associated neuropathy. The pathogenesis of axonal loss in FRDA is still not clear and both hypomyelination and slow axonal degeneration may play a role.