Expanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cells

Expanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cells. Ana M. Silva, Jill M. Brown, Veronica J. Buckle, Richard Wade-Martins and Michele M.P. Lufino; Hum. Mol. Genet. (2015) doi: 10.1093/hmg/ddv096 First published online: March 26, 2015