The promise of futility trials in neurological diseases

The promise of futility trials in neurological diseases. Marcus W. Koch, Lawrence Korngut, David G. Patry, Yahya Agha-Khani, Christopher White, Justyna R. Sarna, Michael Yeung, V. Wee Yong, Daniel Y. C. Heng, Gary Cutter, Luanne Metz; Nature Reviews Neurology (2015) doi:10.1038/nrneurol.2015.34

Basic research into neurological diseases continues to identify candidate therapies faster than they can be tested for their clinical utility, leading to a 'translational gap'.