A study of up to 12 years of follow-up of Friedreich ataxia utilising four measurement tools

A study of up to 12 years of follow-up of Friedreich ataxia utilising four measurement tools. Geneieve Tai, Louise A Corben, Lyle Gurrin, Eppie M Yiu1, Andrew Churchyard, Michael Fahey, Brian Hoare, Sharon Downie, Martin B Delatycki;
J Neurol Neurosurg Psychiatry 2015;86:660-666 doi:10.1136/jnnp-2014-308022

Individuals with larger GAA1 repeat sizes and earlier ages of disease onset were shown to deteriorate at a faster rate and were associated with greater FARS and ICARS scores and lower FIM and MBI scores, which are indicative of greater disease severity.


Link: A study of up to 12 years of follow-up of Friedreich ataxia utilising four measurement tools