Fronto-cerebellar dysfunction and dysconnectivity underlying cognition in friedreich ataxia: The IMAGE-FRDA study

Ian H. Harding1, Louise A. Corben, Elsdon Storey, Gary F. Egan, Monique R. Stagnitti, Govinda R. Poudel, Martin B. Delatycki and Nellie Georgiou-Karistianis. Hum. Brain Mapp.. doi: 10.1002/hbm.23034

These fronto-cerebellar disturbances provide a putative biological basis for the nonmotor symptoms observed in FRDA, and reflect the consequence of localized cerebellar pathology to distributed brain function underlying higher-order cognition


 Fronto-cerebellar dysfunction and dysconnectivity underlying cognition in friedreich ataxia: The IMAGE-FRDA study